Koutou no Hunter Maruya

DeepL Translation:
Early 19th century--Nagasaki. Nagasaki was the only place in Japan that was allowed to trade with the West during the period of national seclusion. Dejima, where all sorts of things from foreign lands were brought in, and sometimes invited "non-human beings" as well...! Mistress Kikuhana of the Maruyama prostitute and her three apprentices take on Nagasaki's avenging outsiders! This is Nagasaki's youkai mystery!

• Someone, please do a better translation of the synopsis.