Honey and Clover

From Viz:
Takemoto lives in a run-down student apartment, where his greatest worry is when he'll next be able to afford to eat meat and whether he'll get to class on time. Although he's away from home and living on his own, Takemoto is far from finished growing up. Along with his crazy cast of friends, Morita, Mayama, Yamada, and Hagumi, Takemoto sets out to discover life and his true self.

Was adapted into a live action film in 2006 and a live action tv series.
In 2003, this manga won the 27th Kodansha Manga Award for shoujo.